Nature Made CholestOFF Plus, 210 Softgels

  • SKU: 660923


  • 900 mg. Plant Sterols And Stanols per Serving
  • Clinically Proven to Lower Cholesterol
  • Take 2 Softgels Twice Daily With Water at Your Two Largest Meals
  • USP Verified

Product Overview

Clinically proved to lower cholesterol†. Click below to learn more.

Nature Made CholestOff® Plus is made with Reducol, a proprietary blend of plant-based sterols and stanols (also called phytosterols). Sterols and stanols work to help reduce cholesterol absorption and reduce LDL (bad) cholesterol in the bloodstream.

CholestOff® Plus is an option for your cholesterol management program, along with a diet low in saturated fat and cholesterol.1 ,2 ‡ One serving of Nature Made CholestOff® Plus supplies 900 mg of plant sterols and stanols for a daily intake of 1800 mg.

  • 900 mg of plant sterols and stanols per serving
  • Clinically proven to lower cholesterol.
  • A safe and effective part of a cholesterol management program.
  • #1 Pharmacist Recommended Vitamin and Supplement Brand*

How does it work?

Plant sterols and stanols, also referred to as the phytosterols, are plant-derived compounds that are similar in structure to cholesterol. Plant sterols and stanols compete with cholesterol for aborption in the digestive tract. As a result, the sterols and stanols help block dietary cholesterol absorption and reduce LDL (“bad”) cholesterol.


The dietary supplement form of phytosterols provides a convenient, easy to take supplement and offers approximately 1.8 grams (1800 mg) of phytosterols per day with a negligible amount of calories. Because many Americans consume as little as about 200 mg per day, this is the amount many Americans need to reach the 2,000 mg per day recommended by the National Institute of Health (NIH) Therapeutic Lifestyle Changes Guidelines.

Food Sources

Plant sterols and stanols occur naturally in small amounts in plant-based foods such as unrefined vegetable oils, whole grains, vegetables, fruits, nuts and legumes. However, in order to meet the recommended guidelines for cholesterol reduction through un-fortified food alone, one would need to consume an excessive amount (e.g. 18 apples or 20 tomatoes daily) of these foods to obtain the recommended 2000 mg of sterols and stanols.


‡Products containing at least 400 mg per serving of plant sterols and stanols, eaten twice a day with meals for a daily intake of at least 800 mg as part of a diet low in saturated fat and cholesterol, may reduce the risk of heart disease. One serving of CholestOff® Plus supplies 900 mg of plant sterols and stanols for a daily intake of 1800 mg.


††Sterols/Stanols are esterified with sunflower oil fatty acids.


*Based on a survey of pharmacists who recommend branded vitamins and supplements.

Supplement Facts

Suggested Use: Adults, take 2 softgels twice daily with water at your two largest meals.

Ingredients: Plant Sterols/Stanols (Pine Tree), Sunflower Oil Esters, Gelatin (Porcine), Glycerin, Medium Chain Triglycerides, Rapeseed Lecithin, Water, Colors Added.

Caution: If you are pregnant, nursing, or taking any medications, consult your physician before use.

No Synthetic Dyes -- Color Derived from Natural Source, No Artificial Flavors, No Preservatives, Gluten Free

Store tightly closed, in a cool, dry place, out of reach of children.

Do not use if imprinted seal under cap is broken or missing.

For Consumer Questions or Inquiries call 1-800-276-2878 or visit